Science-A cargo-sorting DNA robot

A cargo-sorting DNA robot

Anupama J. Thubagere1, Wei Li1, Robert F. Johnson1, Zibo Chen1, Shayan Doroudi2, Yae Lim Lee3, Gregory Izatt2,4, Sarah Wittman2, Niranjan Srinivas4, Damien Woods2,*, Erik Winfree1,2,4, Lulu Qian1,2,†
1. Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA.
2. Computer Science, California Institute of Technology, Pasadena, CA 91125, USA.
3. Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
4. Computation and Neural Systems, California Institute of Technology, Pasadena, CA 91125, USA.
DOI: 10.1126/science.aan6558
© 2017 American Association for the Advancement of Science. All rights Reserved. AAAS is a partner of HINARI, AGORA OARE, PatientInform, CHORUS, CLOCKSS, CrossRef and COUNTER. Science ISSN 1095-9203.

Single-stranded DNA robots with three modular functional domains were designed to move over the surface of a DNA origami sheet and sort molecular cargoes with no additional power input.